

NleG proteins divide and conquer
Pathogenic Escherichia coli strains represent a persistent health risk worldwide, with the enterohemorrhagic E. coli (EHEC) strain O157:H7, in particular, responsible for many outbreaks. During infection of the gastrointestinal tract, EHEC injects pathogenic proteins called “effectors” into cells of the human intestinal lining to subvert normal host processes in benefit of the pathogen. This was another fun and exciting collab with the Alexei Savchenko lab where we investigat