From the bench: New PLoS Pathogens paper is out.
The lab is excited to share our latest research, recently published in PLoS Pathogens. In this work, Sarah Reid-Yu and colleagues showed that the chemokine CXCL9 has direct antimicrobial activity in the gut. This activity, which is independent of its chemotactic properties, protects the gut mucosa from penetration by enteric pathogens. This work supports the importance of a receptor-independent role for chemokines in host defense at mucosal surfaces and may offer alternative treatment strategies for infections, particularly for organisms that are resistant to conventional antibiotics. [Read it here].