Results of a study that we contributed to from the Wright Lab are out today in Nature. “A team of researchers led by McMaster University has discovered a fungus-derived molecule, known as AMA, which is able to disarm one of the most dangerous antibiotic-resistance genes: NDM-1 or New Delhi Metallo-beta-Lactamase-1, identified by the World Health Organization as a global public health threat.” [CBC Story Here].
The latest work from the Coombes lab was recently published in Infection & Immunity. This work was lead by postdoctoral fellow Dr. Joe McPhee, with help from postdoctoral fellow Dr. Cherrie Small, PhD student Sarah Reid-Yu, and collaborators at McGill University. The research investigated how adherent-invasive E. coli, a bacterium associated with Crohn’s disease, breaches host defenses to gain access to the protective layer of epithelial cells in the gut. Using an animal mode